JAK inhibitors are now recommended for patients with inadequate response to at least one csDMARD or bDMARD, or where bDMARDs are not appropriate. Excess mortality was still evident in patients with RA from the BeSt cohort when compared with the healthy, general Dutch population after 17 years of treatment. The major challenge remains to relieve patient symptoms without altering the oncological outcome and a focus on shared decision-making is paramount, Dr Benesova stressed. Petro Machado, London, UK, examined the existing COVID-19 data on risk factors, which suggests the risk for hospitalisation among patients with RMDs is broadly similar to the general population. The link you have selected will take you away from this site to one that is not owned or controlled by Genentech, Inc. Genentech, Inc. makes no representation as to the accuracy of the information contained on sites we do not own or control. Petro Machado, London, UK, examined the existing COVID-19 data on risk factors, which suggests the risk for hospitalisation among patients with RMDs is broadly similar to the general population. For individuals in the US, browse gene.com. This year’s keynote speech on the topic of ‘Innovation for patients with disabilities’ was delivered by Claudio Leverenz. To address this issue, the EULAR Brussels Forum, a digital debate, will be held on 12 October 2020 at 1400 CET to mark World Arthritis Day. Explore disease information across relevant specialties. Safety risks linked to low-dose GC treatment rose with time, becoming significant at 10 years. This indicates that low-dose GC treatment is associated with delayed harmfulness which manifests with increasing cumulative dose. Publish Date February 13, 2020 Updated EULAR Recommendations for Rheumatoid Arthritis Management With DMARDs Rheumatology Advisor Contributing Writer Share on Facebook Share on Twitter Share on LinkedIn Print . Contextual factors are important and contribute to the effect of intra-articular treatment. Welcome to MEDICALLY. The psychological impact of COVID-19 was investigated by Rinie Geenen, Utrecht, The Netherlands, in an online survey comparing worry and stress levels during peak COVID-19 infection in 177 Dutch patients with inflammatory arthritis (IA) versus a similar number of well-matched healthy controls. Learn more about specific developments and new research in rheumatology. It will not be used for any other purpose. Eric Mattheson, Rochester, USA, presented data over the whole of the INBUILD trial, showing that nintedanib had a clinically meaningful effect on the progression of interstitial lung disease (ILD) in patients with autoimmune-related ILDs. This site is intended for US HCPs only. EULAR 2020: BLISS-LN trial results suggest adding belimumab to standard therapy improves renal outcomes in patients with lupus nephritis. This website is intended only for use by US healthcare professionals. Significant and clinically meaningful improvements in all measured outcomes – including strength, activities of daily living performance, well-being, self-efficacy and fatigue – occurred over the 10-week period. It is my sincere pleasure to wel- come you to the EULAR 2020 E-Congress. Dr Sveeas also noted that exercise should be adapted to symptoms such as pain and fatigue. In the current circumstances, social media have almost Please refer to local product information for any medicinal products mentioned. Josef Smolen, Vienna, Austria, reviewed the 2019 updated EULAR recommendations for management of RA, recently published in the June issue of Annals of the Rheumatic Diseases. Please refer to local product information for any medicinal products mentioned. Visiting a rheumatologist within 6 weeks of symptom onset had clear benefits for achieving sustained DMARD-free remission, but not for radiographic progression, said Ellis Neimantsverdriet, Leiden, The Netherlands. Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. Please refer to local product information for any medicinal products mentioned on this website. This content has been independently selected and developed by Springer Healthcare and licensed by Roche for Medically. Two decades after the first annual congress, weare embarked upon a new andexciting course, albeit we wouldhave preferred to meet in person. John Issacs, Newcastle, UK, began this live session with an update on the current COVID-19 situation. Key changes include the addition of a new overarching principle and slight revisions to some recommendations. Patients presenting with arthritis (any joint swelling associated with pain or stiffness) should be referred to, and seen by, a rheumatologist within 6 weeks after onset of symptoms, Patients at risk of persistent arthritis should be started on DMARDs as early as possible (ideally within 3 months) even if they do not fulfil classification criteria for an inflammatory rheumatologic disease. The content on this website may include scientific information about experimental or investigational compounds, indications and services that are not approved or valid in your jurisdiction. CRA EULAR 2020 Update Highlights in a Canadian context With the 2020 EULAR Congress going virtual this year, we are pleased to announce that the Canadian Rheumatology Association (CRA) will be providing members with daily coverage of the E-conference. Older age, comorbidities and moderate-to-high glucocorticoid (GC) use were associated with a higher risk of hospitalisation, while tumour necrosis factor inhibitor (TNFi) treatment decreased the odds. Red flags for participation in exercise for patients with RMDs. No impact on hospitalisation risk was detected with biological therapies, non-steroidal anti-inflammatory drugs or HCQ. The webinar aimed to explain the database's creation, management and functioning, to share preliminary results, and to clarify any questions concerning the … EULAR 2020 Annual Meeting In-depth Report. INDIANAPOLIS, June 3, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) will present new data for Olumiant ® (baricitinib) at the virtual European Congress of Rheumatology (EULAR 2020) taking place June 3-6, 2020.. You can find out more about cookies by browsing our Privacy Policy. Martin Schaefer, Berlin, Germany, analysed the impact of biological DMARDs with different modes of action on fatigue in over 5500 patients from the German Biologics Register, RABBIT (Rheumatoide Arthritis: Boebachtung der Biologika Therapie). In this week's podcast, Drs. - Data from Olumiant recognize the medicine's potential to help patients living with RA and SLE INDIANAPOLIS, June 3, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) will present new data for Olumiant ® (baricitinib) at the virtual European Congress … However, no significant differences in survival outcomes were found between the four therapeutic strategies evaluated. These results may provide a useful insight into overall treatment effectiveness and tolerability and help to promote precision medicine with bDMARDs in real-world settings, Dr Ebina suggested. Effective patient-HCP communication should be applied to enhance adherence. Older age, comorbidities and moderate-to-high use were associated with a higher risk of hospitalisation, while treatment decreased the odds. Although the incidence of treatment-emergent serious AEs was numerically higher in the olokizumab arms versus placebo, no unexpected safety signals occurred. Exercise is considered safe in patients with RMDs and both aerobic and strengthening exercises are recommended. Do not Reliable resources for patients and HCPs regarding COVID-19. Prof McInnes promised delegates an exciting and exceptional experience, centred on a high-calibre scientific programme. The content on this website may include scientific information about experimental or investigational compounds, indications and services that are not approved or valid in your jurisdiction. Laura Martinez-Prat, Barcelona, Spain, presented results from screening panel experiments which have identified anti-protein-arginine deiminase (PAD)1 and PAD6 as novel autoantigens in RA. Obesity was shown to be associated with reduced treatment response to monoclonal antibody TNFi but no association between increased BMI and etanercept response was seen. Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. Intra-articular treatment should be offered in the frame of full individualised information and a shared decision-making process. Zoltan Szekanecz, Debrecen, Hungary, summarised the key drug-related risks of arterial (ATE) and venous thromboembolism (VTE) based on the latest available data from cross-sectional and retrospective analyses. Similarly, the mental well-being of patients with IA did not appear to be adversely affected. For individuals outside the US, browse Roche's patient website or roche.com. When specific expertise or interventions for adherence are needed, they should be made available to patients. Trustmark Globetrotters 2020.Copropriété Sans Syndic 2020,Db Berdan 2020.Half Marathon 2020 Europe,Sacoche 2020,Zene Letöltés 2020.Mal Maas 2020 Start Date,2020 Birding Big Year,Insulation Credit 2020 - 2020 Cng Cars The most common medium for communicating with members was websites with a dedicated COVID-19 area or an FAQs page, while live broadcasts using social media channels and Zoom were key tools for providing support. This … This guidance is now available for researchers when conducting and reporting studies involving work or with work as part of an outcome. The aim of intra-articular treatment is to improve patient-centred outcomes. ©Springer Healthcare 2020. The webinar aimed to explain the database's creation, management and functioning, to share preliminary results, and to clarify any questions concerning the database. Forbius Reported Safety and Initial Anti-Fibrotic Effects of First-in-Class, Selective TGF-beta Inhibitor, AVID200, in Phase 1b Systemic Sclerosis Trial at EULAR 2020 Initial results demonstrate anti-fibrotic effects of AVID200 as indicated by rapid and sustained declines in skin fibrosis. Treatment with olokizumab over a 24-week period was superior to placebo across the primary endpoint (ACR20 response) and secondary endpoints, with onset of efficacy 4–8 weeks after treatment initiation. A total of five overarching principles and 12 recommendations were developed as part of this EULAR project, with the aim of facilitating uniformity and quality of care. Treatment options under evaluation for COVID-19 infection in patients with RMDs. Although recommendations to manage women with rheumatoid arthritis (RA) during the reproductive phase have been established, there is further need for evidence-based information on drug treatment and safety during pregnancy.1 Registries are excellent data sources to address remaining questions. While in the CANTOS study, carried out in the non-rheumatic patients with inflammatory atherosclerosis, the two higher doses of canakinumab reduced the risk of the primary CV endpoint versus placebo. If you are not a healthcare professional, please use the other links below to access information relevant to you. Healthcare professionals outside the US are required to register and log-in to access the full range of content available on this website. Dr Smolen explained that the caveat ‘current practice would be to start a biological DMARD (bDMARD)’ has been removed from recommendation 8 as there is now sufficient data to show Janus kinase (JAK) inhibitors are equivalent to biologics. EULAR remains committed however to meeting its scientific, educational and training obligations. It is hoped this guidance will contribute to high-quality studies which improve healthy and sustainable work participation among patients with IA, Dr Boonen concluded. Learn more about scientific developments and new research in rheumatology disease. EULAR 2020 eCongress delegates receive a 12-month continuing medical education package, including access to Annals of the Rheumatic Diseases. Although the incidence of treatment-emergent serious AEs was numerically 4–8 weeks after treatment initiation. Together with the patient, the HCP should tailor the approach to overcome individual barriers to adherence. Patient global assessment visual analogue scale improvement was largest in the certolizumab group versus placebo with high pre-treatment CNS pain response, explained Jurgen Reich, Erlangen, Germany. Benete Pedersen, Copenhagen, Denmark, explored the acute and long-term anti-inflammatory effects of exercise. Welcome to MEDICALLY. Publish Date June 16, 2020 EULAR Recommendations for Rheumatic Disease Management During the COVID-19 Pandemic Meghna Rao Share on Facebook Share on Twitter Share on LinkedIn Share on Reddit Print Share by . 2020 EULAR Congress Portal until September 2020, giving a great opportunity to those who could not join live to login and check the presentations at your convenience. That is according to findings from a study presented at the EULAR 2020 E-Congress in a press release dated 3 rd June 2020. Two decades after the first annual congress, weare embarked upon a new andexciting course, albeit we wouldhave preferred to meet in person. EULAR 2020: Lilly Shares New Data for Olumiant® in Rheumatoid Arthritis and Systemic Lupus Erythematosus INDIANAPOLIS, June 3, 2020 /PRNewswire/ -- Eli … Souzi Makri, Limassol, Cyprus, reviewed the important issue of where to find reliable information on COVID-19 and highlighted a number of key sources for use by both physicians and patients. Treatment with IL-6 inhibitors significantly increased the chance of attaining low fatigue levels within 6 months. All exercise should incorporate a warm and cool-down session and should progress slowly, with gradual increases in exercise load, duration and frequency. I am a healthcare professional On May 15 th 2020, EULAR hosted a webinar on the EULAR COVID-19 Database for rheumatologists and other clinicians. As part of this live bench-to-bedside session, Yuliya Kurochkina, Novosibrisk, Russian Federation presented findings from a study investigating the mechanism of action of dexamethasone-modified dendritic cells (dexDCs) in 20 patients with RA. Therapeutic strategies evaluated in patients with RA in the BeSt cohort, An estimated proportion of adults with RA who are overweight or obese. The EULAR Recommendations session was one of the highlights of this year’s congress. Jade Skeates, Corsham, UK, presented results from a 10-week trial evaluating a progressive resistance training programme (PRTP) in patients with IA. EULAR RheumaMap: Unmet needs in 2020 The RheumaMap has been updated in 2019. The perceived knowledge and skills gap for UK physicians is higher than that of their German and US counterparts - and educational interventions are needed to plug this. Points to consider when incorporating the perspective of young patients with IA into patient-reported outcome measures (PROMs) were reviewed by Paul Studenic, Vienna, Austria. Dr Gossec explained that the treatment landscape in PsA is now rich in new therapies and updated guidelines aim to integrate all available drugs into a graduated management approach. One of the final sessions of this year’s congress was devoted to the EULAR Project on non-adherence, an important issue given that an estimated 30–80% of patients with RMD are non-adherent to their current treatment regimen. The increased risk of GIP might be explained by an increased risk of diverticulitis with misleading clinical presentation, said study author Claire Rempenault, Montpellier, France. Marieke Voshnaar, Enschede, The Netherlands, described medication adherence in RA as an interplay of barriers and facilitators. This conclusion was based on an analysis of two observational European cohorts which investigated evidence for the first EULAR recommendations on early RA. The models developed were able to identify patients at risk of serious infection, myocardial infarction and stroke, and may help pave the way towards more personalised care. No impact on hospitalisation risk was detected with biological therapies, non-steroidal anti-inflammatory drugs or HCQ. Flare rate remained low in patients with long-standing RA remission treated with stable TNFi doses but increased steeply (by over 50%) when tapering to withdrawal. However, the level of perceived stress due to the pandemic (although increased versus normal) was found to be comparable in both groups. Date: 3-6 June 2020 Venue: Messe, Frankfurt Applications have now closed. EULAR 2020 E-Congress Date 03.06.20–06.06.20 Citation EMJ Rheumatol. Watch EULAR 2020 ‘live’ Many of the scientific programme sessions can be viewed live, starting offwith the Opening Plenary session onWednesday, 3 June, and ending with thealways popular EULAR Recommendations2020 session on Saturday, 6 June. In this activity, Cytokine Signalling Inhibitors: Update from EULAR 2020, international experts review and discuss key abstracts and data from EULAR 2020 specifically relating to … Find out about the unmet needs in rheumatology in this latest edition. Wilfred Peter, Leiden, Netherlands, discussed issues around the implementation of high intensity exercise in patients with RMD. The EULAR 2020 Scientific Programme will start on Wednesday, 3 June 2020 EULAR 2020 will cover the broad spectrum of the rheumatic diseases and include state-of-the-art lectures, basic science and clinical symposia, abstract sessions, presentations and discussions of difficult cases, workshops and special interest group sessions. If you are not a healthcare professional, please use the other links below to access information relevant to you. Both tools and training are needed to improve the open discussion of adherence issues and their effective management. If you wish to restrict or block cookies, which are set on your device, then you can do this through your browser settings. Information available on this website does not constitute professional medical advice, and Roche and Genentech accept no responsibility for access to or use of the same. medwireNews: Adding belimumab to standard therapy improves renal outcomes among patients with lupus nephritis, indicate findings from the BLISS-LN trial presented at the EULAR 2020 E-Congress. This website is intended for healthcare professionals outside the United Kingdom (UK). Patient education should be provided for people with RMDs as an integral part of standard care. Intra-articular treatments are recommended and widely used in the management of joint diseases. Iam EULAR E-CONGRESS 2020 Dear Sir/Madam, Thank you for reading this guide. Karolina Benesova, Heidelberg, Germany, outlined recommendations on rheumatic immune-related adverse events (AEs) due to cancer immunotherapy - a newly recognised disease entity within the rheumatology sphere. You can find out more about cookies by browsing our Privacy Policy. Dr Issacs explained that COVID-19 is ‘much more than just a lung disease’, causing a broad range of symptoms and affecting multiple organ systems. Stay up to date with the latest scientific information from international medical congresses. Roche and Genentech do not support, endorse or recommend the unapproved use of any compound or service in your jurisdiction, including those discussed on this website. About EULAR 2021 Congress The aim of the European Congress of Rheumatology is to provide a forum of the highest standard for scientific (both clinical and basic), educational and social exchange between professionals involved in rheumatology, liaising with patient organizations, in order to achieve progress in the clinical care of people with rheumatic diseases. It is my sincere pleasure to wel- come you to the EULAR 2020 E-Congress. There are clinically relevant differences in performance between the immunofluorescence assay and scintillation proximity assay, he explained, although neither is superior to the other. John Weinman, London, UK, explained that medication non-adherence remains a major issue in RA but one which clinicians can play a key role in identifying and improving. APLAR 2020 will provide a forum for exchange on cutting edge scientific and clinical information across multiple disciplines such as rheumatology, physiotherapy, nursing and allied health. 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